The FDA announced changes to the labeling for epinephrine auto-injectors to help patients and caregivers use the medication appropriately in the event of anaphylaxis (anna-fih-LACK-sis). Anaphylaxis is a serious allergic reaction. Epinephrine is always the first treatment for serious allergic reactions.
For all epinephrine auto-injectors:
- Hold the patient's leg and keep the leg steady while you inject the epinephrine
This will help prevent the needles from cutting the thigh or becoming stuck in the skin. A study published last year found that in most cases involving cuts or stuck needles, a child kicked his or her leg while getting epinephrine. The risk of injury is minimized when the leg is held steady.
See a doctor for infection signs or symptoms at the injection site, such as:
- persistent redness
For EpiPen® and EpiPen Jr® auto-injectors only:
- When you inject, hold the the EpiPen firmly in place for 3 seconds.
The labeling change that says three seconds is enough time to keep the auto-injector in the outer thigh. Previous instructions said to hold the EpiPen in place for ten seconds.
Last year, Kids With Food Allergies advised these steps to help avoid injury:
- Place the child flat on their back.
- If just one adult is available, that person should firmly hold the child’s leg at, or just above, the knee with one hand. They should then use their other hand to use the auto-injector in the outer thigh of that leg.
- If more adults are available, one person should firmly hold both of the patient’s ankles to prevent kicking. Another person should stay near the child’s head to help keep them calm. The third person should use the auto-injector in the child’s outer thigh.
- Never re-insert an auto-injector needle. Each needle should only be used once. If the needle comes out of the leg before you finish, do not re-insert it. If you think the dose was not given, use a second auto-injector to try again.
- Keep in mind that using the auto-injector takes less force than you think. The instructions on the EpiPen, for example, say to “swing and firmly push” against the outer thigh. This does not need to be a very forceful motion. The pressure from pressing firmly against the thigh will activate the device.
- You need to practice – No matter which device you use, practice is very important. This is why most packages of these medications include “training devices.” These training devices do not contain needles or medicine. If you are using a generic auto-injector that does not include a trainer, check the company website for a video. Or call them to order trainers.
If you have any questions, speak with your healthcare professional.
Medical Review June 2016.