Food Allergy Awareness: Oral Food Challenges Diagnose Food Allergy

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The experts recommend using oral food challenges under physician supervision for diagnosing food allergy.  The double-blind, placebo-controlled food challenge is the “gold standard.”  However, a single-blind or open food challenge may be considered diagnostic under certain circumstances: If either of these challenges elicit no symptoms (that is, the food challenge is negative), then food allergy can be ruled out; but when either challenge elicits objective symptoms (that is, the challenge is positive) and those objective symptoms correlate with medical history and are supported by laboratory tests, then the diagnosis of food allergy are supported.  


Source: NIH Publication, Guidelines for the Diagnosis and Management of Food Allergy in the United States: Summary for Patients, Families, and Caregivers. (Download PDF)

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