Tagged With "oral immunotherapy"

Blog Post

Omalizumab Makes Oral Immunotherapy Treatments More Effective

Kids With Food Allergies ·
Combining a 16-week initial course of the medication omalizumab with oral immunotherapy (OIT) greatly improves the efficacy of OIT for children with allergies to multiple foods, new clinical trial findings show. After 36 weeks, more than 80 percent of children who received omalizumab and OIT could safely consume two-gram portions of at least two foods to which they were allergic, compared with only a third of children who received placebo and OIT.
Blog Post

Parents Give Variety of Reasons for Putting Off Food Challenges

KFA News Team ·
What causes parents to delay an oral food challenge for their children?   An oral food challenge (OFC) is the only way to determine whether a food allergy exists. Sometimes both the child and the parent can be nervous about eating a food they...
Blog Post

FREE Webinar: Oral Food Challenges: What to Expect

Kids With Food Allergies ·
RSVP:   Reserve your seat by registering   WHEN:  Tuesday, July 28, 2015   TIME:  1 PM - 2 PM Eastern time   WHERE:  Your computer, iOS or Android device   An oral food challenge in a medical setting is the main...
Blog Post

Will Oral Food Challenges or Accidental Ingestions Make Your Child's Food Allergy Worse?

KFA News Team ·
If your child accidentally eats the food they avoid, will their food allergy last longer? What about purposely eating the food during an in-office food challenge? Have you avoided in-office food challenges because you’re afraid a reaction will make the allergy worse? A recently published study can put your mind at ease. What the study was about Researchers followed a group of 512 infants allergic to milk and egg . These babies also had a strong likelihood for peanut allergy. The researchers...
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Re: Will Oral Food Challenges or Accidental Ingestions Make Your Child's Food Allergy Worse?

Paula Tarpley (Lucy) ·
No, I can't insurance because this is the insurance through my husbands work. There is no way I'm going to be able to do a food challenge at home. I'm way too frightened of what could happen but what else is one to do when you know that at some point you have to know?! Talked with doctor today (left message) and asked if there is a way around it. They wouldn't even pay for the skin or blood allergy test. It's crazy! Our insurance is amazing and we've had 14 years. Never had to use the...
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Re: Will Oral Food Challenges or Accidental Ingestions Make Your Child's Food Allergy Worse?

kandicejo ·
I can't even wrap my head around an insurance that won't cover allergy stuff Allergies are such a widespread condition that can lead to time off work, etc. Hopefully the doctor has some good guidance for what you can do.
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Re: Will Oral Food Challenges or Accidental Ingestions Make Your Child's Food Allergy Worse?

Paula Tarpley (Lucy) ·
I'm hoping to hear something back! Praying they can come up with something different that my insurance will pay for. I can go to an allergist and pay my co-pay but when they want to start the testing, that's where my insurance stops! It ridiculous and I'm so upset about this. I know doctors can around it, some will and some won't. Hopefully I have one that will and can! Thank you all for your support! I don't have family or friends so it's difficult to deal with all by yourself.
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Re: Will Oral Food Challenges or Accidental Ingestions Make Your Child's Food Allergy Worse?

Paula Tarpley (Lucy) ·
Meant to say, "Don't have family or friends around!" Our families live in different states. We moved here when my husband got transferred.
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Re: Will Oral Food Challenges or Accidental Ingestions Make Your Child's Food Allergy Worse?

Heidi B ·
Hi Paula, hopefully you find an allergist that you like and trust. Be upfront with the Doctor about the insurance issues and your concerns. Some allergists - not all - will allow patients to come and sit in the waiting room while the food is ingested. I hope you find one that you can work with. The other thing is, the allergy tests run about $1,500 depending on how many foods you're running. You may find that the cost is worth it?
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Re: Will Oral Food Challenges or Accidental Ingestions Make Your Child's Food Allergy Worse?

Paula Tarpley (Lucy) ·
I hate that my insurance doesn't cover the allergy testing or the food challenge. Which leaves me with no choice but to do home challenges. This is very scary for me! What else can be done?
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Re: Will Oral Food Challenges or Accidental Ingestions Make Your Child's Food Allergy Worse?

Kathy P ·
That is very scary. It's important to do oral food challenges in a medically supervised setting with immediate availability of medical support/intervention in the event of a reaction. Your insurance won't cover any type of allergy testing? Neither skin or blood testing?
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Re: Will Oral Food Challenges or Accidental Ingestions Make Your Child's Food Allergy Worse?

Jen ·
That's frustrating, Paula. Would you consider switching insurance companies when it's open enrollment?
Blog Post

Q&A: What Does Omalizumab Mean for Oral Immunotherapy Treatment for Multiple Food Allergies?

Kids With Food Allergies ·
Oral immunotherapy (OIT) is a proposed method to treat food allergy. It is currently in late-stage clinical trials (peanut specifically). It is expected to be approved by the U.S. Food and Drug Administration (FDA) soon. There have been many clinical trials for specific food OIT alone and with medicines, such as omalizumab, as reported in this study.
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Re: Q&A: What Does Omalizumab Mean for Oral Immunotherapy Treatment for Multiple Food Allergies?

APV ·
Omalizumab is manufactured using Chinese hamster ovary (CHO) cells and is therefore contaminated with numerous CHO proteins. It is well documented that patients start developing anti-drug antibodies (ADA) against monoclonal antibody treatments such as omalizumab. This can result in drug ineffectiveness. More worrisome is antibodies created against CHO. It is well known from cancer research that immunization with homologous xenogeneic proteins (injection of animal proteins like CHO, that...
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Re: Q&A: What Does Omalizumab Mean for Oral Immunotherapy Treatment for Multiple Food Allergies?

APV ·
It must be clarified that OIT is not a cure. It is changing the disease state. IgE is naturally involved in helminth defense (worm infections). A "low intensity" worm infection is IgE dominated. This is equivalent to food allergy. A "high intensity" worm infection is IgG4 dominated (high IgG4/IgE) ratio. This is equivalent to a person with food allergy who has received OIT. In food allergy, your immune system has been programmed to recognize food items as worms. So continued food allergen...
Blog Post

Patients Taking Lower Maintenance Doses of Peanut Oral Immunotherapy May Still Achieve Desensitization

KFA News Team ·
Oral immunotherapy (OIT) is a treatment that could potentially help peanut allergic patients achieve desensitization, but some patients are unable to tolerate maintenance doses that are large enough to facilitate unlimited peanut consumption.
Blog Post

Itchy Mouth After Eating Fruits and Vegetables?

Kids With Food Allergies ·
Do you or your child get an itchy mouth after eating fresh fruits? Dr. Vaishali  Mankad explains oral allergy syndrome, food allergy and pollen allergy cross-reactivity: CROSS-REACTIVITY BETWEEN POLLEN AND FOODS (POLLEN-FOOD SYNDROME OR ORAL...
Blog Post

FDA Allows Peanut Immunotherapy Treatments to Advance

KFA News Team ·
  The Food and Drug Administration (FDA) agreed to expedite the review of a specially formulated peanut product. The peanut product, called AR101, is being studied as a potential allergy treatment. The status was granted after the company...
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Re: Itchy Mouth After Eating Fruits and Vegetables?

BerCake ·
My 5 year old is allergic to citrus.
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Re: Itchy Mouth After Eating Fruits and Vegetables?

Kathy P ·
Is your 5yo IgE allergic to citrus or OAS/cross reactive allergic to citrus? My ds was allergic to citrus as a toddler, but outgrew it. But it was not OAS since it was systemic/gi symptoms.
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Re: Itchy Mouth After Eating Fruits and Vegetables?

nlar4 ·
I have birch pollen OAS-- a pain, like food allergies, but easier to manage.
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Re: Itchy Mouth After Eating Fruits and Vegetables?

Kathy P ·
We deal w/ OAS here too - easier to manage in that it likely wont' result in a severe reaction, but it means so many more foods to avoid.
Blog Post

Study of Australian Children Points to Possible Clue in Curing Peanut Allergy

Kids With Food Allergies ·
Australian researchers say they may have come up with a potential treatment for peanut allergy that combines eating peanuts with a probiotic. More studies are needed and parents should not try this at home, the scientists say. Probiotics are sometimes...
Blog Post

Milk Allergy Study Shows People with Asthma Should Be Included in Food Allergy Research

Kids With Food Allergies ·
A recent study showed some success in treating milk-allergic asthmatics with oral immunotherapy.   The authors suggested that future studies include people with asthma. That's because people with food allergies and asthma have a higher risk for...
Blog Post

Food Allergy Treatments Show Promising Results

KFA News Team ·
A report from NBCNews explains two new treatments being studied: multiple food oral immunotherapy and a new skin patch. The treatments involve exposing the patient to a small amount of their allergen and slowly increasing the dose to build up...
Blog Post

EoE Developed in Patients with IgE-Mediated Food Allergy After OIT

Kids With Food Allergies ·
Eosinophilic esophagitis occurred in nearly 3% of patients with immunoglobulin E-mediated food allergy who had undergone oral immunotherapy in a recent study.   Read the full article on Healio: EoE developed in patients with IgE-mediated food...
Blog Post

Food Allergy Awareness: Oral Food Challenges Diagnose Food Allergy

Kids With Food Allergies ·
Did you know?  The experts recommend using oral food challenges under physician supervision for diagnosing food allergy.  The double-blind, placebo-controlled food challenge is the “gold standard.”  However, a...
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Re: EoE Developed in Patients with IgE-Mediated Food Allergy After OIT

SBilliel ·
Thanks for posting this!
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Re: Food Allergy Treatments Show Promising Results

josephine ·
As a mother of a son (age 11) who has been dealing with this allergy combo. since one, I agree with this article. We also have contact and air borne to same which just adds to it all. The important thing to remember is to read, read and read and know about everything that goes into your child's mouth. Cooking things at home is major too. My dream is that they will find a cure to all food allergies and to find resturants that actually can come up with something for my child to eat besides...
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Re: Study of Australian Children Points to Possible Clue in Curing Peanut Allergy

RW ·
Thank you for sharing the citation. I read the abstract as the full text wasn't available. They did not control for peanut component, just skin test wheal size. I wonder why since such a difference has been shown with the components... I'd like to open up a question too as I noticed the study included very young children. I'm a mom with a peanut allergic kid and I want there to be research done, but I'm in an ethical conundrum when it comes to putting my kid in a study. I'm just not sure it...
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Re: Study of Australian Children Points to Possible Clue in Curing Peanut Allergy

Allison ·
Hmmm. Good question! I'm not a doctor, but I can throw out some theories based on conversations I have had with doctors, plus my family's own experience with medical studies. I'm thinking that there may be a difference in how food allergy works or presents in children vs. adults, so the results would not be the same. Logistically, depending on the study, visits may require you to see a doctor somewhat often - it varies on the study. One I just looked at was every two weeks. If you work FT...
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Re: Study of Australian Children Points to Possible Clue in Curing Peanut Allergy

RW ·
Thanks for your thoughtful response! We parents are faced with some difficult choices aren't we? How did you discover you child was allergic to things like mustard and chickpeas? My kid is swearing a Twizzler made her throat hurt, but she's not real trustworthy right now, she eats another flavor of them all the time and the ingredients are identical. I thin she didn't like this flavor and wanted the "yummy medicine" like her brother had moments before when dinner made his mouth itch. We are...
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Re: Study of Australian Children Points to Possible Clue in Curing Peanut Allergy

Allison ·
Mustard - he had a hot dog, which included it as a hidden spice. He threw it up within the hour and had profuse rhinitis as well (sneezing/discharge from nose). We added that to the testing list at his next appointment. Chick peas, I honestly don't remember, it was so long ago. It may have been a rash around his mouth and itchiness. Shellfish is new. He was eating shrimp ok. He didn't really like it but I chopped it up small and gave it to him about once a month. Then I sort of fell off that...
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Re: Study of Australian Children Points to Possible Clue in Curing Peanut Allergy

RW ·
Wow! What a tough journey. I love shrimp but am kind of afraid to try it with my kid. We had a bad experience with trying TN at home. I would advise your friend with the PN daughter to take it in careful steps. I thought my DD was PN only and gave her almonds, it went fine. Then I gave her cashews and we called 911.... First step is peanut component blood test. Apparently there are several different proteins in the peanut one can be allergic to. Some proteins track towards "outgrowing" it,...
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Re: Study of Australian Children Points to Possible Clue in Curing Peanut Allergy

Kathy P ·
Yes, there is what is called "component testing" which can help predict the chances of outgrowing and/or passing an oral challenge based on which proteins you react to. All tree nuts are lumped together, but botanically/allergenically, there are different categories. The big problems is that they are all often processed together making everything cross contaminated. That's why a lot will recommend avoiding all tree nuts and peanuts if you are allergic even to just one. The chances of cross...
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Re: Study of Australian Children Points to Possible Clue in Curing Peanut Allergy

RW ·
She is 6 and loves cooking with me. She's also a great reader and we practice with labels. One thing I've wondered.... Do you know of a book that teaches kids the different names of nuts in a fun way? I learned by eating them, but when you avoid nuts it is hard to teach a kid all the names and shapes to be alert for. Thanks for all the feedback. I can't tell you how much I appreciate this website.
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Re: Study of Australian Children Points to Possible Clue in Curing Peanut Allergy

Kathy P ·
I don't know of any, but maybe others have some ideas. You will get more input if you ask that question on the Main forum .
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Re: Study of Australian Children Points to Possible Clue in Curing Peanut Allergy

Allison ·
I recently conducted a fake food tour via the Internet of various cheeses and nuts my son had to look out for. You could use Google Images.... We used to have a book but it was aimed at toddlers - I can't remember the name of the top of my head.
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Re: Study of Australian Children Points to Possible Clue in Curing Peanut Allergy

RW ·
Is this a published study and do you have a citation? All I can find are new clips like this (that will probably get kids sent to the hospital.)I can't tell from any of the articles I've read say if the study was controlled for peanut component since kids are allergic to different proteins. I also wonder what the side effects were to ingesting that much bacteria. Gut flora is an ecosystem of it's own, and disrupting it may have consequences.
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Re: Study of Australian Children Points to Possible Clue in Curing Peanut Allergy

Allison ·
Hi, thank you for noticing! This is the citation; I read the study and I don't recall if they looked at different components, I would have to check again. We tried to make it clear that this is really just a first step and that parents should never, ever attempt to replicate medical studies at home! The citation is: Administration of a probiotic with peanut oral immunotherapy: A randomized trial Tang, Mimi L.K. et al. Journal of Allergy and Clinical Immunology A press release to the research...
Blog Post

Certain Egg Allergy Patients Still Have Tolerance Five Years After OIT

KFA News Team ·
A study presented at the 2019 Annual Meeting of the American Academy of Allergy, Asthma & Immunology (AAAAI) has found that certain patients treated with egg oral immunotherapy (OIT) are likely to continue consuming and tolerating egg five years after treatment.
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Re: Certain Egg Allergy Patients Still Have Tolerance Five Years After OIT

kandicejo ·
It's so great to see research for egg allergy!
Blog Post

Study Shows It May Be Possible to Eat Peanut Regularly Years After OIT

KFA News Team ·
A lot of questions remain about long-term allergy outcomes following immunotherapy. A new study presented at the 2019 American Academy of Allergy, Asthma & Immunology (AAAAI) Annual Meeting has found that the ability to incorporate peanut food equivalents into the diet is maintained years after completing food immunotherapy.
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Re: Study Shows It May Be Possible to Eat Peanut Regularly Years After OIT

ColoradoCarol ·
Articles about OIT in the news has been the bane of my existence. Every single new person I meet and tell about my son’s food allergies brings up OIT like I’ve never heard of it. And they dismiss his allergies like if I would just do OIT for him, he would be magically cured. Implication is that I’m either an idiot or a bad mom. As you all know, there are a lot of caveats with these studies. And OIT is nowhere near ready for prime time, as in everyone being able to do it or be cured by it. My...
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Re: Study Shows It May Be Possible to Eat Peanut Regularly Years After OIT

K8sMom2002 ·
Carol, you're certainly NOT a bad mom ... and so very far from being an idiot! Not every treatment for ANY disorder, including food allergies, is right for every person. Each family has to figure out the benefits and risks that are unique to their own situation. You're being careful and doing your due diligence and making the best decisions for your family.
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Asthma and Allergy Foundation of America Responds to Premature ICER Review of New Peanut Allergy Treatments

Kids With Food Allergies ·
The Asthma and Allergy Foundation of America (AAFA) addresses concerns regarding the Final Evidence Report assessing the clinical effectiveness and value of treatments for peanut allergy released by the Institute for Clinical and Economic Review (ICER) on July 10, 2019. ICER’s report may cause concern for the allergy community that the findings will restrict access to new treatments for peanut allergy.
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Pairing Xolair (Omalizumab) with Oral Immunotherapy Improves Outcome for Milk Allergy

Kids With Food Allergies ·
Pairing Oral Immunotherapy with Biological Medication for Allergic Asthma Reduces Dosing-Related Side Effects and Time Needed to Reach Maintenance Dose   SAN DIEGO, CA – Omalizumab is an immunomodulator medication, which means it acts...
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Treatment Hope for Those with Multiple Food Allergies

Kids With Food Allergies ·
Asthma drug aids simultaneous desensitization to several food allergies, study finds "An asthma drug accelerates the process of desensitizing patients with food allergies to several foods at the same time, a new study by researchers at the Stanford...
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Oral Milk Allergy Therapy Loses Power Over Time

Kids With Food Allergies ·
Robert Wood, MD, of Johns Hopkins University, presented research at the American Academy of Allergy, Asthma, and Immunology (AAAAI) meeting last week that warns of the effects of oral milk allergy immunotherapy. "Among children who underwent oral...
Kids With Food Allergies
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